Cat allergens are the second most common cause of indoor allergies, after dust mites. Fel d 1 is the main allergen produced by cats in their saliva and sebaceous glands. Fel d 1 is responsible for most cat-related allergic reactions. This model shows Fel d 1 bound to a neutralizing IgG antibody that can block allergic responses. It supports research into allergen-specific immunotherapy and the development of biologics to prevent allergic symptoms.

Molecule Name(s): Fel d 1 & neutralizing IgG antibody

Source: Cats (Felis catus) and human (Homo sapien)

Associated Allergies: Pet allergies

References: PDB entry 5VYF

Pink: IgG light chain (Chain A)

Purple: IgG heavy chain (Chain B)

Green: Fel d 1 (Chain C)