December 15, 2025

Version: 2.0.0

What's New?

The NIH 3D website has undergone a major update to improve performance, maintainability, and long-term support. This release includes:

• A full migration of the site framework from Vue.js to React
• A redesigned user interface, with improved layout, navigation, and consistency across pages
• A new 3D viewer offering smoother interaction and enhanced rendering
• Initial support for WebXR, enabling immersive VR exploration of compatible models

What does this mean for users?

While the site may look slightly different, all core features remain present and intuitive to access. Users can expect:

• A more responsive and stable experience across all devices
• Clearer navigation, with some elements moved for improved usability
• A modernized model-viewing experience in both standard and immersive modes
• The ability to launch WebXR directly from supported model pages using compatible VR headsets and browsers

December 08, 2025

Version: 1.30

What's New?

• Internal system enhancements and security updates.

November 28, 2025

Version: 1.29

What's New?

• Internal system enhancements and security updates.

October 23, 2025

Version: 1.28

What's New?

• Internal system enhancements and security updates.

September 30, 2025

Version: 1.27

What's New?

• Internal system enhancements and security updates.

September 02, 2025

Version: 1.26

What's New?

• Internal system enhancements.

July 31, 2025

Version: 1.25

What's New?

• Updated "No Fear Act Data" link.
• Updated FAQs page.

June 26, 2025

Version: 1.24

What's New?

• Added Submitted and Published dates to the entry page.
• Updated the Terms and Conditions page.
• Internal system enhancements.

May 29, 2025

Version: 1.23

What's New?

• Removed the ability to add a biography during account registration.
• Added six new sub-collections to the 3D Pollen Library collection.
• Grasses, rushes and sedges
• Woody plants
• Flowering fruiting plants
• Mosses & Ferns
• Common weeds
• Common herbs
• Internal system enhancements and security updates.

April 24th, 2025

Version: 1.22

What's New?

• Added a new collection: Allergy
• Added three sub-collections to e-NABLE.
  • Recommended Models
  • Tested Models
  • Community Designs

March 27th, 2025

Version: 1.21

What's New?

• Fixed PubMed citation references.
• Internal system enhancements and security updates.

February 27th, 2025

Version: 1.20

What's New?

• Internal system enhancements and security updates.

January 30th, 2025

Version: 1.19

What's New?

• For medical image files with a .zip extension, the anonymization process should only be executed if the archive contains .dcm files.
• File downloading will only create a zip archive if the output contains more than one file.

January 16th, 2025

Version: 1.18

What's New?

• UI/UX improvements, security updates, and minor bug fixes

November 13th, 2024

Version: 1.17

What's New?

AlphaFold Enhancements:

AlphaFold Quick Submit Functionality:Enables direct access to the AlphaFold Protein Structure Database via UniProt ID, streamlining workflows for protein structure submissions.

Implemented Features:

• 3D Structure Generation Options:Full-sequence predictions and high-confidence views highlighting regions with high pLDDT scores, available in both ribbon and surface styles.
• Confidence Metric Visualizations:pLDDT coloring for per-residue confidence, PAE coloring for alignment accuracy, and molecular representations like rainbow coloring, secondary structure, hydropathy, and coulombic views.
• Output Formats:Supports multiple 3D formats (.glb, .stl, .wrl, .x3d) to meet diverse usage needs.
• Thumbnail Previews:Auto-generated for all visualization modes to enhance browsing.
• Surf-Vis and Surf-Print Models:Introduces optimized "surf-vis" models for web and VR, and high-resolution "surf-print" models for 3D printing. Users may reprocess existing entries to apply these improvements.

Download Enhancements:

• Streamlined UI & Filtering:Modern design with filter options for file type, style, color, printability, and AlphaFold status.
• Batch Selection & Sorting:“Select All” and extension-specific selection options for quick batch downloads. Files organized into sections for easy browsing.
• Improved Download Modal:Summary of selected files with Terms and Conditions acknowledgment for easy review.
• Enhanced User Experience:Floating "Download Files" button, faster file loading, responsive interactions, and better error notifications.

November 5th, 2024

Version: 1.16

What's New?

• Includes minor updates to the user interface, enhancing overall usability. No major feature changes have been made.

June 28th, 2024

Version: 1.14

What's New?

1. Increased Download Timeout: Extended the timeout duration for downloads from 65 seconds to 10 minutes, ensuring larger files can be downloaded without interruption.
2. Enhanced Error Handling: Updated error handling mechanisms to provide user notifications on the download modal, keeping users informed of any issues encountered during the download process.
3. Download Progress Indicator: Improved the download modal to display progress messages, indicating the amount of data downloaded, offering better transparency and user experience.
4. Retry Logic for Lambda Invocations: Implemented retry logic for lambda invocations to enhance the reliability and robustness of the application, reducing the likelihood of failures during critical operations.
5. Improved "What's Next" Page: Added a more informative "What's next" page after DOI requests for entries, guiding users on the subsequent steps.
6. DOI Request Option on Receipt Page: Added an option to request DOIs on the receipt page after publishing entries, offering a streamlined process for users to obtain DOIs for their contributions.

June 4th, 2024

Version: 1.13

What's New?

1. Upgrade of Vue. This upgrade includes several bug fixes and performance improvements.
2. Internal system enhancements and security updates.

April 25th, 2024

Version: 1.12

What's New?

1. Feature the Human Reference Atlas collection on Homepage.
2. ACorrected the label of the "UNIPROT ID" field in entries to "UNIPROT ACCESSION" for clarity and accuracy.
3. Resolved the issue where the mesh repair toggle wasn't working for Quick Submit.
4. Fixed a bug where builds erroneously showed "User did not provide image" on the Discover page, even when images were provided.
5. Additional Web Application Firewall (WAF) rules have been applied to enhance platform security.

March 28th, 2024

Version: 1.11

What's New?

1. UI/UX improvements, security updates, and minor bug fixes

March 5th, 2024

Version: 1.10

What's New?

1. Release of the Human Reference Atlas 3D Reference Object Library collection
2. Enable uploads of filenames with spaces
3. Download and parse the full mmCIF file for PDB metadata
4. Various admin feature implementations, security updates, and minor bug fixes

February 1st, 2024

Version: 1.09

What's New?

1. Bug fix with re-running file workflows after mesh repair option change
2. Adjustments to PDB CIF parsing
3. Third party package updates for security remediations
4. Various UI/UX improvements and admin function additions

January 4th, 2024

Version: 1.08

What's New?

1. Changes to Terms and Conditions
2. Change reduction factor value in DICOM workflows
3. Use full 3DPX id in DOI URL
4. Addition of automated tests

November 22nd, 2023

Version: 1.07

What's New?

1. Added the "TB in 3D" sub-collection under the "TB Portals Models" collection
2. Added the "Amgueddfa Cymru, National Museum Wales, palynology collection" sub-collection under the "3D Pollen Library" collection
3. Updated the NIH 3D homepage to show the TB in 3D model
4. Implemented an automated email to users upon submitting a DOI request form
5. Added controls to restrict certain special characters in uploaded file names
6. Backend updates for upcoming features and UI/UX improvements

November 8th, 2023

Version: 1.06

What's New?

1. Added a new feature that allows users to request DOIs for their published models
2. Backfilled DOIs for the newest version of all existing Quick Submit models
3. Updated the database to support new ontologies structure for an upcoming feature
4. Made backend updates for upcoming features and small bug fixes

August 31st, 2023

Version: 1.05

What's New?

1. Implemented collection of entry view counts by users.
2. Entry published dates are saved as a searchable field.
3. Back-end additions for upcoming features and small bug fixes.

July 27th, 2023

Version: 1.04

What's New?

1. Introduced the new VA collection.
2. Added download counts to the entry pages.
3. Updated the FAQ page.
4. Various UI/UX improvements, security remediations, and small bug fixes.

July 13th, 2023

Version: 1.03

What's New?

1. Improvements to the sign-in experience. Users are automatically redirected to their target page on sign-in.
2. Back-end collection of file sizes, checksums, download counts, and published date for upcoming features.
3. Compression of user uploaded thumbnails to improve page load time.
4. Capture of quick-submit source files through ChimeraX for future reproducibility.
5. Fixed redirects to NIH 3D user profile pages originating from 3DPX URLs.
6. Added new controls to the model viewer. Users have the ability to toggle between surface and wireframe and have the option to switch screen space ambient occlusion (SSAO) on/off.
7. Increased the computing resources available to the API and front-end.
8. Various UI/UX improvements and small bug fixes.

May 12th, 2023

Version: 1.02

What's New?

This release features a reworking of our sign-in system to fix some unusual behavior that was reported by testers. We are also happy to introduce the new TB Portals Collection and the 3D Pollen Library.

Numerous other UI improvements, search updates, and workflow optimizations are also included in this release.

1. Updated sign-in session information access by UI components
2. Added individualized filters and full-text search to each collection.
3. Added an alternate data-grid style display to the user submission dashboard
4. Added iconography, warnings, and policy updates in accordance NIAID external link policies
5. Numerous minor accessibility improvements in response to Deque Axe scans
6. Implemented WYSIWIG editor for larger full text input areas
7. Creation of Pollen and TB Portals Collections
8. Added new search index fields to CloudSearch. You can now search by molecular ID from the full-text search bar
9. Added molecular weight calculations for non-Quick Submit entries that go through the ChimeraX workflow
10. Autogenerate file descriptions for non-Quick Submit entries running through ChimeraX workflow
11. Updated vertex and poly count computation method
12. Allow multiple PDB, EMDB, and Uniprot IDs in post-submission wizard
13. Added more options to Experimental Methods ontology
14. Corrected discrepancies in migration data from 3D print exchange
15. Various UI/UX improvements and small bug fixes

March 7th, 2023

Version: 1.0

What's New?

Welcome to the first official release for NIH 3D!

Everything!

1. The the 3D Print Exchange has been rebuilt from scratch and re-branded as NIH 3D
2. Site philosophy has been changed to embrace the upload and output of files that are suitable for 3D Printing AND/OR for other visualization technologies (eg. AR, VR, Animation...)
3. All input files, metadata, and x3d outputs have been migrated from the NIH 3D Print Exchange. We have also migrated the .zip outputs that package the .wrl, .x3d and .stl files. In some cases we had to modify entries in order to be accomodated by our new system. If this required a file replacement, the original file has been attached as supplementary data. In some cases files were renamed but the data left untouched, in which case the old file was not included in the supplementary data.
4. User accounts from 3D Print Exchange have only been migrated if the user had created models or builds, commented on the site, or been listed as a contributor to a 3D Print Exchange Entry. This was part of an effort to remove spam accounts from the site. You can easily create a new account from the sign-in
5. You may now create an account using Google Sign-In OR e-mail/password
6. All 3D Print Exchange entries have been stored as v1.0, then the input files have been re-run through our new workflows to generate v2.0. You may notice differences bewteen the outputs on 3D Print Exchange and NIH 3D due to changes in the software underlying our workflows
7. New and Improved Workflows
   • Moved from Chimera to Chimera X for generation of 3D models for Quick Submit and molecular data files
   • Output several new 3D printable and non-3D printable representations of molecules
   • Our DICOM workflows use Simple ITK and VTK to generate bone models from CT data
   • DICOMs and any supplementary medical imaging files will be anonymized automatically.
   • Now accept and output GLB format files
   • Custom "mesh repair" solution for 3D Printing has been built in Blender.
8. Completely redesigned submission and post-submission process for models and builds
9. Modernized UI
10. Robust Search Features
11. Expanded list of metadata pulled from external databases for "Quick Submit"
12. Expanded list of metadata for users to annotate their entries
13. Re-classification of models into new NIH 3D Categories: Biomacromolecules, Viruses, Small Molecules, Prosthetics, Anatomy, and Cells & Organelles

We expect to continuously be adding new features to the site, so stay tuned!

If you notice a problem with your entry in it's new state on NIH 3D, please contact us and we will repair it for you.