Bet v 1 is the main allergen in birch pollen and one of the most studied pollen allergens worldwide. This model shows its flexible structure and internal hydrophobic cavity, which may influence how it interacts with the immune system. Bet v 1 is also known for causing cross-reactions with certain fruits and vegetables, making it important for understanding both seasonal and oral allergy syndrome. (See NIH 3D - Birch Pollen Food Syndrome entry in the Food Allergy sub-collection)

Molecule Name(s): Bet v 1

Source: Birch trees (Betula pendula)

Biological Role: Binds small ligands like fatty acids, flavonoids, and cytokinins

Associated Allergies: Seasonal pollen allergies

References: PDB entries 1BV1