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NIH3D

SARS-CoV-2 spike protein 6VSB with one Receptor Binding Domain (RBD) up in the active conformation

Created by
cruzp2
Created:
4/29/20
Submitted:
3/6/23
Published:
3/6/23

Select an image below to view

3DPX-014102

Licensing:

CC-BY
98
17
Version 2

Category

Biomacromolecules
Biomacromolecules

Collection(s)

Description

SARS-CoV-2 spike protein from 6VSB.  The protomer that has its Receptor Binding Domain (RBD) flipped into the up (active) conformation has its domains colored as described in Figure 1 of: Wrapp, D.Wang, N.Corbett, K.S.Goldsmith, J.A.Hsieh, C.L.Abiona, O.Graham, B.S.McLellan, J.S. (2020) Science 367: 1260-1263

 

Blue: N-Terminal Domain (NTD)

Green: Receptor Binding Domain (RBD)

Tan: Remainder of S1

Cyan: Fusion Peptide

Yellow: Heptad Repeat 1

Orange: Central Helix

Purple: Connector Domain

Red: Remainder of S2

 

See also 3dpx-012877 for a related structure from SARS-CoV with all RBD down in the inactive conformation.