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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Lumacaftor

PubChem 16678941
was used by NIH 3D workflows to automatically generate models for
Philipp
Created:
3/10/26
Submitted:
3/10/26
Published:
3/10/26
ball and stick, print caution
16678941-bas-color-print_NIH3DAtoms shown as ball-and-stick with standard colors. 3D printable, with caution, using certain 3D printers

Select an image below to view

ball and stick, print cautionball and stick, repaired for 3D printingsticks, not intended for 3D printingsticks, not intended for 3D printingsticks, print cautionsticks, repaired for 3D printingspace-filled, print cautionspace-filled, repaired for 3D printingsticks, print cautionball and stick, print cautionspace-filled, print caution
3DPX-023367

NIH 3D DOI:

https://doi.org/10.60705/3dpx/23367.1

Licensing:

CC-BY
How to cite this NIH 3D entry
38
6
Version 1

Category

Small Molecules
Small Molecules
Description
Lumacaftor is an aromatic amide obtained by formal condensation of the carboxy group of 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid with the aromatic amino group of 3-(6-amino-3-methylpyridin-2-yl)benzoic acid. Used for the treatment of cystic fibrosis. It has a role as a CFTR potentiator and an orphan drug. It is a member of benzoic acids, a member of pyridines, an organofluorine compound, a member of benzodioxoles, a member of cyclopropanes and an aromatic amide.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=16678941&width=400&height=400