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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Lumacaftor

PubChem 16678941
was used by NIH 3D workflows to automatically generate models for
Philipp
Created:
3/10/26
Submitted:
10/7/26
Published:
10/7/26
ball-and-stick, color, print caution
16678941-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-023367

NIH 3D DOI:

https://doi.org/10.60705/3dpx/23367.2

Licensing:

CC-BY
How to cite this NIH 3D entry
150
69
Version 2

Category

Small Molecules
Small Molecules
Description
Lumacaftor is an aromatic amide obtained by formal condensation of the carboxy group of 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid with the aromatic amino group of 3-(6-amino-3-methylpyridin-2-yl)benzoic acid. Used for the treatment of cystic fibrosis. It has a role as a CFTR potentiator and an orphan drug. It is a member of benzoic acids, a member of pyridines, an organofluorine compound, a member of benzodioxoles, a member of cyclopropanes and an aromatic amide.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=16678941&width=400&height=400