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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Bictegravir

PubChem 90311989
was used by NIH 3D workflows to automatically generate models for
Cyrus Nouroozi
Created:
10/8/25
Submitted:
10/7/26
Published:
10/7/26
ball-and-stick, color, print caution
90311989-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-022991

NIH 3D DOI:

https://doi.org/10.60705/3dpx/22991.2

Licensing:

CC-BY
How to cite this NIH 3D entry
196
83
Version 2

Category

Small Molecules
Small Molecules
Description
Bictegravir is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2R,5S,13aR)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxylic acid with the amino group of 2,4,6-trifluorobenzylamine. It is a second-generation integrase strand transfer inhibitor (INSTI) and used (as its sodium salt) for the treatment of HIV-1. It has a role as a HIV-1 integrase inhibitor. It is a secondary carboxamide, a monocarboxylic acid amide, an organic heterotetracyclic compound and a trifluorobenzene. It is a conjugate acid of a bictegravir(1-).
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=90311989&width=400&height=400