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NIH3D

Capsazepine

PubChem 2733484
was used by NIH 3D workflows to automatically generate models for
Noheli Moreno
Created:
9/27/25
Submitted:
10/7/26
Published:
10/7/26

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Learn more about NIH 3D workflow outputs

3DPX-022969

Licensing:

CC-BY
212
69
Version 2

Category

Small Molecules
Small Molecules
Description

Capsazepine is a benzazepine that is 2,3,4,5-tetrahydro-1H-2-benzazepine which is substituted by hydroxy groups at positions 7 and 8 and on the nitrogen atom by a 2-(p-chlorophenyl)ethylaminothiocarbonyl group. A synthetic analogue of capsaicin, it was the first reported capsaicin receptor antagonist. It has a role as a capsaicin receptor antagonist. It is a member of catechols, a benzazepine, a member of thioureas and a member of monochlorobenzenes.
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=2733484&width=400&height=400