Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock () or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

National Institute of Allergy and Infectious Disease
NIH 3D
FAQsBioArt

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock () or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

NIH3D

HIV-1 TAR RNA/NEOMYCIN B COMPLEX

Generated by NIH 3D workflows using data provided by
cass condray
Created:
6/21/25
Submitted:
10/9/26
Published:
10/9/26
HIV-1 TAR RNA/NEOMYCIN B COMPLEX. thin ribbon, rainbow
1qd3-ribbon-thin-rainbowHIV-1 TAR RNA/NEOMYCIN B COMPLEX. Thin ribbon representation colored by rainbow from N-terminus (red) to C-terminus (blue).

Select an image below to view

HIV-1 TAR RNA/NEOMYCIN B COMPLEX. thin ribbon, rainbowHIV-1 TAR RNA/NEOMYCIN B COMPLEX. thin ribbon, by chainHIV-1 TAR RNA/NEOMYCIN B COMPLEX. thin ribbon, no color

HIV-1 TAR RNA/NEOMYCIN B COMPLEX. lo-res mol surface, by chainHIV-1 TAR RNA/NEOMYCIN B COMPLEX. lo-res mol surface, no colorHIV-1 TAR RNA/NEOMYCIN B COMPLEX. hi-res mol surface, by chain, print cautionHIV-1 TAR RNA/NEOMYCIN B COMPLEX. hi-res mol surface, no color, print caution

Learn more about NIH 3D workflow outputs

3DPX-022174

Licensing:

CC-BY
How to cite this NIH 3D entry
94
55
Version 2

Category

Biomacromolecules
Biomacromolecules
Description

Binding of human immunodeficiency virus type 1 (HIV-1) transactivator (Tat) protein to Tat-responsive RNA (TAR) is essential for viral replication and is considered a promising starting point for the design of anti-HIV drugs. NMR spectroscopy indicated that the aminoglycosides neomycin B and ribostamycin bind to TAR and that neomycin is able to inhibit Tat binding to TAR. 

Source Data Details