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NIH3D

HIV-1 RNA A-RICH HAIRPIN LOOP

Generated by NIH 3D workflows using data provided by
cass condray
Created:
6/20/25
Submitted:
6/20/25
Published:
6/20/25

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3DPX-022173

Licensing:

CC-BY
15
0
Version 1

Category

Biomacromolecules
Biomacromolecules
Description

Interaction of HIV-1 genomic RNA and human tRNA(Lys)3 initiates viral reverse transcription. An adenosine-rich (A-rich) loop in HIV RNA mediates complex formation between tRNA and viral RNA. We have determined the structure of an A-rich loop oligonucleotide using nuclear magnetic resonance spectroscopy