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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Low-density Lipoprotein Receptor-Related Protein 1B (LRP1B)

Generated by NIH 3D workflows using data provided by
Jeff Miller
Created:
5/16/25
Submitted:
5/11/25
Published:
5/16/25
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AF-Q53S26-F1-model_v4-ribbon-secondary-vis_NIH3DRibbon representation colored by secondary structure (a-helix: blue, B-sheet: red, coil: yellow). Not intended for 3D Printing

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3DPX-021930

Licensing:

Public Domain
How to cite this NIH 3D entry
54
4
Version 1

Category

Biomacromolecules
Biomacromolecules
Description

Low-density lipoprotein receptor-related protein 1B (LRP1B) is a member of the LDL receptor family, and is involved in receptor-mediated endocytosis. It also plays roles in cell migration, tumor suppression, and signal transduction. LRP1B interacts with various intracellular proteins and can participate in signal transduction pathways, impacting processes like cell growth, migration, and DNA damage response. LRP1B is considered a candidate tumor suppressor gene and is frequently inactivated in various cancers, including lung cancer.


Source Data Details