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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Glycogen Synthase Kinase 3 beta

Generated by NIH 3D workflows using data provided by Jeff Miller
Created:
5/16/25
Submitted:
5/11/25
Published:
5/16/25
3D View
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AF-Q9YH60-F1-model_v4-ribbon-secondary-vis_NIH3DRibbon representation colored by secondary structure (a-helix: blue, B-sheet: red, coil: yellow). Not intended for 3D Printing

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3DPX-021924

Licensing:

Public Domain
How to cite this NIH 3D entry
22
2
Version 1
Description

Glycogen synthase kinase 3 beta (GSK3B), is a multi-functional serine/threonine kinase that regulates glucose homeostasis, cell signaling, and neuronal function. It typically acts as a negative regulator, often inhibiting various cellular pathways and processes. GSK3B is a key component in various signaling pathways, including the Wnt signaling pathway, where it phosphorylates beta-catenin, leading to its degradation and inhibition of Wnt signaling.



Category

Biomacromolecules
Biomacromolecules
Source Data Details