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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Glycogen Synthase Kinase 3 beta

Generated by NIH 3D workflows using data provided by
Jeff Miller
Created:
5/16/25
Submitted:
10/9/26
Published:
10/9/26
GSK-3. thin ribbon, secondary structure
af-q9yh60-f1-model_v4-ribbon-thin-secondaryGSK-3. Thin ribbon representation colored by secondary structure (a-helix: blue, B-sheet: red, coil: yellow).

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GSK-3. thin ribbon, secondary structureGSK-3. thin ribbon, rainbowGSK-3. thin ribbon, by chainGSK-3. thin ribbon, no colorGSK-3. thick ribbon, secondary structure, print cautionGSK-3. thick ribbon, rainbow, print cautionGSK-3. thick ribbon, by chain, print cautionGSK-3. thick ribbon, no color, NIH 3D repaired

GSK-3. lo-res mol surface, by chainGSK-3. lo-res mol surface, hydrophobicityGSK-3. lo-res mol surface, coulombicGSK-3. lo-res mol surface, no colorGSK-3. hi-res mol surface, by chain, print cautionGSK-3. hi-res mol surface, hydrophobicity, print cautionGSK-3. hi-res mol surface, coulombic, print cautionGSK-3. hi-res mol surface, no color, print caution

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3DPX-021924

Licensing:

Public Domain
How to cite this NIH 3D entry
215
205
Version 2

Category

Biomacromolecules
Biomacromolecules
Description

Glycogen synthase kinase 3 beta (GSK3B), is a multi-functional serine/threonine kinase that regulates glucose homeostasis, cell signaling, and neuronal function. It typically acts as a negative regulator, often inhibiting various cellular pathways and processes. GSK3B is a key component in various signaling pathways, including the Wnt signaling pathway, where it phosphorylates beta-catenin, leading to its degradation and inhibition of Wnt signaling.



Source Data Details