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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Bcl-2 family member protein

Generated by NIH 3D workflows using data provided by
Jeff Miller
Created:
5/16/25
Submitted:
10/9/26
Published:
10/9/26
Bcl-2 family protein. thin ribbon, secondary structure
af-e7pj43-f1-model_v4-ribbon-thin-secondaryBcl-2 family protein. Thin ribbon representation colored by secondary structure (a-helix: blue, B-sheet: red, coil: yellow).

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Bcl-2 family protein. thin ribbon, secondary structureBcl-2 family protein. thin ribbon, rainbowBcl-2 family protein. thin ribbon, by chainBcl-2 family protein. thin ribbon, no colorBcl-2 family protein. thick ribbon, secondary structure, print cautionBcl-2 family protein. thick ribbon, rainbow, print cautionBcl-2 family protein. thick ribbon, by chain, print cautionBcl-2 family protein. thick ribbon, no color, NIH 3D repaired

Bcl-2 family protein. lo-res mol surface, by chainBcl-2 family protein. lo-res mol surface, hydrophobicityBcl-2 family protein. lo-res mol surface, coulombicBcl-2 family protein. lo-res mol surface, no colorBcl-2 family protein. hi-res mol surface, by chain, print cautionBcl-2 family protein. hi-res mol surface, hydrophobicity, print cautionBcl-2 family protein. hi-res mol surface, coulombic, print cautionBcl-2 family protein. hi-res mol surface, no color, print caution

Learn more about NIH 3D workflow outputs

3DPX-021921

Licensing:

Public Domain
How to cite this NIH 3D entry
115
78
Version 2

Category

Biomacromolecules
Biomacromolecules
Description

The Bcl-2 family of proteins plays a crucial role in regulating apoptosis, or programmed cell death, and cellular survival. These proteins can be broadly classified into pro-apoptotic and anti-apoptotic members. Bcl-2 proteins primarily promote cell survival by inhibiting apoptosis. They achieve this by directly interacting with and antagonizing pro-apoptotic proteins, like Bax and Bak, which are key effectors of apoptosis.


Source Data Details