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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Low-density lipoprotein receptor-related protein 6 (LRP6) isoform X6

Generated by NIH 3D workflows using data provided by
Jeff Miller
Created:
5/16/25
Submitted:
5/10/25
Published:
5/16/25
ribbon , colored by secondary structure, not intended for 3D printing
AF-A0A455BDJ9-F1-model_v4-ribbon-secondary-vis_NIH3DRibbon representation colored by secondary structure (a-helix: blue, B-sheet: red, coil: yellow). Not intended for 3D Printing

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surface, colored by by chain, not intended for 3D printingsurface, colored by hydrophobicity, not intended for 3D printingsurface, colored by local charge, not intended for 3D printingsurface, not intended for 3D printingsurface, colored by by chain, print cautionsurface, colored by hydrophobicity, print cautionsurface, colored by local charge, print cautionsurface, print caution
3DPX-021919

Licensing:

Public Domain
How to cite this NIH 3D entry
21
2
Version 1

Category

Biomacromolecules
Biomacromolecules
Description

3D AlphaFold model of low-density lipoprotein receptor-related protein 6 (LRP6) from Physeter macrocephalus. LRP6 is a transmembrane protein that acts as a co-receptor for the Wnt signaling pathway. It plays a crucial role in various physiological processes, including embryonic development, bone formation, and stem cell homeostasis. LRP6 also influences lipid metabolism, glucose homeostasis, and cardiovascular health.


Source Data Details