Beta-catenin (CTNNB1)
Generated by NIH 3D workflows using data provided by
Jeff Miller
Created:
5/10/25
Submitted:
10/9/26
Published:
10/9/26
Select an image below to view
Learn more about NIH 3D workflow outputs
Category
Description
3D model of human beta-catenin. Beta-catenin plays a crucial role in both cell-cell adhesion and cell signaling, particularly within the Wnt signaling pathway. It's a key component of adherens junctions that link cell surface cadherin proteins to the actin cytoskeleton. Additionally, beta-catenin acts as a core effector of the Wnt/beta-catenin signaling pathway, where upon activation of the pathway, it translocates to the nucleus and acts as a transcriptional co-activator.
