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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Beta-catenin (CTNNB1)

Generated by NIH 3D workflows using data provided by
Jeff Miller
Created:
5/10/25
Submitted:
5/10/25
Published:
5/10/25
ribbon , colored by secondary structure, not intended for 3D printing
AF-A0A2R8Y804-F1-model_v4-ribbon-secondary-vis_NIH3DRibbon representation colored by secondary structure (a-helix: blue, B-sheet: red, coil: yellow). Not intended for 3D Printing

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3DPX-021913

Licensing:

Public Domain
How to cite this NIH 3D entry
27
1
Version 1

Category

Biomacromolecules
Biomacromolecules
Description

3D model of human beta-catenin. Beta-catenin plays a crucial role in both cell-cell adhesion and cell signaling, particularly within the Wnt signaling pathway. It's a key component of adherens junctions that link cell surface cadherin proteins to the actin cytoskeleton. Additionally, beta-catenin acts as a core effector of the Wnt/beta-catenin signaling pathway, where upon activation of the pathway, it translocates to the nucleus and acts as a transcriptional co-activator.


Source Data Details