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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Roflumilast

PubChem 449193
was used by NIH 3D workflows to automatically generate models for
Jon Bell
Created:
6/26/24
Submitted:
10/9/26
Published:
10/9/26
ball-and-stick, color, print caution
449193-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-021244

NIH 3D DOI:

https://doi.org/10.60705/3dpx/21244.2

Licensing:

CC-BY
How to cite this NIH 3D entry
349
45
Version 2

Category

Small Molecules
Small Molecules
Description
Roflumilast is a benzamide obtained by formal condensation of the carboxy group of 3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzoic acid with the amino group of 3,5-dichloropyridin-4-amine. Used for treatment of bronchial asthma and chronic obstructive pulmonary disease. It has a role as an anti-asthmatic drug and a phosphodiesterase IV inhibitor. It is a member of benzamides, an aromatic ether, an organofluorine compound, a chloropyridine and a member of cyclopropanes.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=449193&width=400&height=400