This intracranial aneurysm model was developed by Dr. Joshua Pfefer’s group in FDA as a tissue-simulating phantom for evaluating neurosurgical imaging systems that detect indocyanine green (ICG) fluorescence. It is comprised of eleven files of cerebral tissue structures that can be assembled into a biomimetic model that simulates ICG angiography procedures when printed with an appropriate fluorophore-doped photopolymer resin.

The model was fabricated using a stereolithography 3D‐printer (Form2, Formlabs, Inc., Somerville, MA, USA) based on UV-curing of customized methacrylate photopolymer resin composites well‐matched with human brain optical properties.  Additional relevant details can be found in a prior publication  (https://doi.org/10.1117/12.2579357).

Tissue areas simulated include:

Brain Stem

Cranial Nerves

Grey Matter

Dura Mater

Cranial Arteries 

File listing:

BA Big Vessel.stl 

PCom Big Vessel.stl

Grey Matter 1.stl       

Brainstem and Cranial Nerves.stl

Dura Tent.stl