Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock () or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

National Institute of Allergy and Infectious Disease
NIH 3D
FAQsBioArt

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock () or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

NIH3D

Crystal structures of human MEK1 with carboxamide-based allosteric inhibitor XL518 (GDC-0973), or related analogs.

PDB 4AN2
was used by NIH 3D workflows to automatically generate models for
Nuclear Juicer
Created:
6/27/22
Submitted:
10/8/26
Published:
10/8/26
thin ribbon, secondary structure
4an2-ribbon-thin-secondaryThin ribbon representation colored by secondary structure (a-helix: blue, B-sheet: red, coil: yellow).

Select an image below to view

thin ribbon, secondary structurethin ribbon, rainbowthin ribbon, by chainthin ribbon, no colorthick ribbon, secondary structure, print cautionthick ribbon, rainbow, print cautionthick ribbon, by chain, print cautionthick ribbon, no color, NIH 3D repaired

lo-res mol surface, by chainlo-res mol surface, hydrophobicitylo-res mol surface, coulombiclo-res mol surface, no colorhi-res mol surface, by chain, print cautionhi-res mol surface, hydrophobicity, print cautionhi-res mol surface, coulombic, print cautionhi-res mol surface, no color, print caution

Learn more about NIH 3D workflow outputs

3DPX-017294

NIH 3D DOI:

https://doi.org/10.60705/3dpx/17294.3

Licensing:

CC-BY
How to cite this NIH 3D entry
177
9
Version 3

Category

Biomacromolecules
Biomacromolecules
Description
PDB Classification: TRANSFERASE
Source Data Details
Attribution Instructions