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National Institute of Allergy and Infectious Disease
NIH 3D
FAQsBioArt

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NIH3D

Pacritinib

PubChem 46216796
was used by NIH 3D workflows to automatically generate models for
Glyphosate
Created:
4/1/22
Submitted:
10/8/26
Published:
10/8/26
ball-and-stick, color, print caution
46216796-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-017010

NIH 3D DOI:

https://doi.org/10.60705/3dpx/17010.3

Licensing:

CC-BY
How to cite this NIH 3D entry
244
16
Version 3

Category

Small Molecules
Small Molecules
Description
Pacritinib is an azamacrocycle with formula C28H32N4O3. It is a Janus kinase inhibitor and its citrate salt is approved for the treatment of intermediate or high risk, primary or secondary myelofibrosis. It has a role as an antineoplastic agent, an anti-inflammatory agent, an apoptosis inducer and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a member of benzenes, a cyclic ether, a member of pyrrolidines and an azamacrocycle. It is a conjugate base of a pacritinib(1+).
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=46216796&width=400&height=400