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National Institute of Allergy and Infectious Disease
NIH 3D
FAQsBioArt

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NIH3D

Sotorasib

PubChem 137278711
was used by NIH 3D workflows to automatically generate models for
Joytsai
Created:
12/15/21
Submitted:
10/8/26
Published:
10/8/26
ball-and-stick, color, print caution
137278711-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-016519

NIH 3D DOI:

https://doi.org/10.60705/3dpx/16519.3

Licensing:

CC-BY
How to cite this NIH 3D entry
235
17
Version 3

Category

Small Molecules
Small Molecules
Description
Sotorasib is a pyridopyrimidine that is pyrido[2,3-d]pyrimidin-2(1H)-one substituted by 4-methyl-2-(propan-2-yl)pyridin-3-yl, (2S)-2-methyl-4-(prop-2-enoyl)piperazin-1-yl, fluoro and 2-fluoro-6-hydroxyphenyl groups at positions 1, 4, 6 and 7, respectively. It is approved for the treatment of patients with non-small cell lung cancer having KRASG12C mutations. It has a role as an antineoplastic agent. It is a tertiary carboxamide, a member of acrylamides, a member of methylpyridines, a member of phenols, a pyridopyrimidine, a N-acylpiperazine, a tertiary amino compound and a member of monofluorobenzenes.
Source Data Details
Sotorasib v2

3DPX-021042

by Joytsai

Sotorasib v2