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NIH3D

Hepatitis B Relaxed Circular DNA, condensed (PathogenAR)

Created by
kbrowne
Created:
7/23/21
Submitted:
10/8/26
Published:
10/8/26

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Learn more about NIH 3D workflow outputs

3DPX-015990

Licensing:

CC-BY
567
20
Version 5

Category

Biomacromolecules
Biomacromolecules

Collection(s)

Description

This model approximates RC DNA when folded inside the capsid.

The RC DNA was built by snapping a curve path to the interior of the capsid surface in Maya, then shrinking it to provide some extra space.  ~3200bp of DNA was then created along the path using Molecular Maya's dsDNA Rigging Kit (https://clarafi.com/training/intro-mmaya-dsdna-kit).  RT from HIV was used as a very general approximation of P Protein as a structure was not available. PDB 1T03</color> was fitted to the RC DNA and bases were removed from the strand as appropriate.

This model was used in the PathogenAR Hepatitis B: The Hepatitis B Life Cycle Module in PathogenAR (https://www.niaid.nih.gov/research/pathogenar-mobile-app)