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NIH3D

Hepatitis B Relaxed Circular DNA (PathogenAR)

Created by
kbrowne
Created:
7/23/21
Submitted:
8/16/23
Published:
8/16/23

Select an image below to view

3DPX-015988

Licensing:

CC-BY
123
3
Version 3

Category

Biomacromolecules
Biomacromolecules

Collection(s)

Description

The RC DNA was built with Molecular Maya's dsDNA Rigging Kit (https://clarafi.com/training/intro-mmaya-dsdna-kit/).  Approximately 3200bp of DNA were created along a circular path, then bases were removed/added as necessary.   RT from HIV (PDB 1T03) was used as a very general approximation of P Protein as a structure was not available.

An illustration of the life cycle from PathogenAR is included, with the step associated with this model highlighted.

This model was used in the PathogenAR Hepatitis B: The Hepatitis B Life Cycle Module in PathogenAR (https://www.niaid.nih.gov/research/pathogenar-mobile-app)

Life cycle diagram highlighted where model is relevant
Zbrush rendering of model