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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Crystal structure of a human gamma-aminobutyric acid receptor, the GABA(A)R-beta3 homopentamer

Generated by NIH 3D workflows using data provided by
Tropicco
Created:
6/21/21
Submitted:
3/6/23
Published:
3/6/23
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3DPX-015878

Licensing:

CC-BY
How to cite this NIH 3D entry
160
29
Version 2

Category

Biomacromolecules
Biomacromolecules
Description

Type-A γ-aminobutyric acid receptors (GABAARs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain. A decline in GABAAR signalling triggers hyperactive neurological disorders such as insomnia, anxiety and epilepsy.

Source Data Details
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