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NIH3D

Acadesine

PubChem 17513
was used by NIH 3D workflows to automatically generate models for
thannich
Created:
6/7/21
Submitted:
3/6/23
Published:
3/6/23

Select an image below to view

3DPX-015831

Licensing:

CC-BY
51
1
Version 2

Category

Small Molecules
Small Molecules
Description

Acadesine is a 1-ribosylimidazolecarboxamide in which the carboxamide group is situated at position 4 of the imidazole ring, which is further substituted at position 5 by an amino group. A purine nucleoside analogue and activator of AMP-activated protein kinase, it is is used for the treatment of acute lymphoblastic leukemia and is reported to have cardioprotective effects. It has a role as a platelet aggregation inhibitor and an antineoplastic agent. It is an aminoimidazole, a nucleoside analogue and a 1-ribosylimidazolecarboxamide.