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National Institute of Allergy and Infectious Disease
NIH 3D
FAQsBioArt

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NIH3D

Bisantrene

PubChem 5351322
was used by NIH 3D workflows to automatically generate models for
gscho
Created:
3/27/21
Submitted:
10/8/26
Published:
10/8/26
ball-and-stick, color, print caution
5351322-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-015595

NIH 3D DOI:

https://doi.org/10.60705/3dpx/15595.3

Licensing:

CC-BY
How to cite this NIH 3D entry
202
17
Version 3

Category

Small Molecules
Small Molecules
Description
Bisantrene is an anthracenyl bishydrazone with antineoplastic activity. Bisantrene intercalates with and disrupts the configuration of DNA, resulting in DNA single-strand breaks, DNA-protein crosslinking, and inhibition of DNA replication. This agent is similar to doxorubicin in activity, but unlike doxorubicin, does not exhibit cardiotoxicity. (NCI04)
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=5351322&width=400&height=400