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NIH3D

5,7-Dihydroxy-8-[(3R,4S)-3-hydroxy-1-methylpiperidin-4-yl]-2-methylchromen-4-one

PubChem 13422573
was used by NIH 3D workflows to automatically generate models for
rajnish.kumar@ki.se
Created:
11/11/20
Submitted:
3/6/23
Published:
3/6/23

Select an image below to view

3DPX-015084

Licensing:

CC-BY
46
1
Version 2

Category

Small Molecules
Small Molecules
Description

Rohitukine is a member of the class of chromones that is 4H-chromen-4-one in which the hydrogens at positions 2,5,7 and 8 are replaced by methyl, hydroxy, hydroxy, and (3S,4R)-3-hydroxy-1-methylpiperidin-4-yl groups, respectively. It is an alkaloid initially isolated from Amoora rohituka and is a precursor of the anti-cancer compound flavopiridol. It has a role as a plant metabolite, an antineoplastic agent, an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor, a fungal metabolite, an anti-inflammatory agent, an anti-ulcer drug, an anticholesteremic drug and an antileishmanial agent. It is a hydroxypiperidine, a tertiary amino compound, a member of chromones, a member of resorcinols and an alkaloid.
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=13422573&width=400&height=400
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=13422573&width=400&height=400