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NIH3D

Rohitukine

PubChem 13422573
was used by NIH 3D workflows to automatically generate models for
rajnish.kumar@ki.se
Created:
11/11/20
Submitted:
10/8/26
Published:
10/8/26

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Learn more about NIH 3D workflow outputs

3DPX-015084

Licensing:

CC-BY
200
17
Version 3

Category

Small Molecules
Small Molecules
Description

Rohitukine is a member of the class of chromones that is 4H-chromen-4-one in which the hydrogens at positions 2,5,7 and 8 are replaced by methyl, hydroxy, hydroxy, and (3S,4R)-3-hydroxy-1-methylpiperidin-4-yl groups, respectively. It is an alkaloid initially isolated from Amoora rohituka and is a precursor of the anti-cancer compound flavopiridol. It has a role as an antineoplastic agent, an anticholesteremic drug, an anti-ulcer drug, an anti-inflammatory agent, an antileishmanial agent, a plant metabolite, a fungal metabolite and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is an alkaloid, a member of chromones, a member of resorcinols, a hydroxypiperidine and a tertiary amino compound.
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=13422573&width=400&height=400