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NIH3D

Talazoparib

PubChem 135565082
was used by NIH 3D workflows to automatically generate models for
buffavaholic
Created:
10/27/20
Submitted:
10/8/26
Published:
10/8/26

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3DPX-015007

Licensing:

CC-BY
218
17
Version 3

Category

Small Molecules
Small Molecules
Description

Talazoparib is an orally available small molecule inhibitor of the DNA repair enzyme poly ADP-ribose polymerase (PARP) which is used as an antineoplastic agent in the treatment of selected cases of breast cancer. Talazoparib is associated with a moderate rate of serum aminotransferase elevations during therapy and is suspected to cause rare instances of clinically apparent acute liver injury.
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=135565082&width=400&height=400