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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

SARS-CoV-2 Open Spike (S-Protein) with Ab fragment (PathogenAR)

Created by
kbrowne
Created:
9/11/20
Submitted:
10/8/26
Published:
10/8/26
GLB with textures applied
antibodyGLB with textures applied.

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3DPX-014826

Licensing:

CC-BY
How to cite this NIH 3D entry
602
53
Version 5

Category

Biomacromolecules
Biomacromolecules

Collection(s)

Pathogen AR
Pathogen AR
Description

This SARS-CoV-2 Spike (S) protein in the open conformation is bound to an antibody fragment to illustrate how antibodies can interfere with S protein's ability to bind ACE2.

The antibody structure was added to the scene using data from PDB 6XCM.  The RBD from this model was aligned to the open RBD from PDB 6VSB_1_1_1 (http://www.charmm-gui.org/?doc=archive&lib=covid19).

Source Data Details