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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Remdesivir

PubChem 121304016
was used by NIH 3D workflows to automatically generate models for
Mathew Hale
Created:
6/2/20
Submitted:
10/8/26
Published:
10/8/26
ball-and-stick, color, print caution
121304016-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-014482

NIH 3D DOI:

https://doi.org/10.60705/3dpx/14482.3

Licensing:

CC-BY
How to cite this NIH 3D entry
272
19
Version 3

Category

Small Molecules
Small Molecules
Description
Remdesivir is a carboxylic ester resulting from the formal condensation of the carboxy group of N-[(S)-{[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl]methoxy}(phenoxy)phosphoryl]-L-alanine with the hydroxy group of 2-ethylbutan-1-ol. A broad-spectrum antiviral prodrug with potent in vitro antiviral activity against a diverse panel of RNA viruses such as Ebola virus, MERS-CoV and SARS-CoV. It is currently in Phase III clinical trials for the treatment of Covid-19 in adults. It has a role as an anticoronaviral agent, an antiviral drug and a prodrug. It is a nitrile, a phosphoramidate ester, a carboxylic ester, an aromatic amine, a C-nucleoside and a pyrrolotriazine. It is functionally related to a GS-441524.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=121304016&width=400&height=400