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NIH3D

Hemagglutinin 1 (HA1) Influenza - PathogenAR

Created by
kbrowne
Created:
4/2/20
Submitted:
3/6/23
Published:
3/6/23

Select an image below to view

3DPX-013411

Licensing:

CC-BY
250
14
Version 2

Category

Biomacromolecules
Biomacromolecules

Collection(s)

Description

This model was created for PathogenAR, an augmented reality program being developed by the Biovisualization Program in the Bioinformatics and Computational Biosciences Branch in the Office of Cyber Infrastructure and Computational Biology at NIAID.

Influenza Hemagglutinin (HA) is a protein required to infect host cells residing the respiratory tract.  It first binds to sialic acid on the surface of target cells, then mediates fusion of the viral and target cell membranes.  This results in viral RNA being released into the host cell.   An effective vaccine would stimulate the immune system to produce antibodies which bind to the regions of HA responsible for these functions.   This model includes antibodies bound to sites in the stem and head regions.

Included Files:

The "App Version" of the model is included as a .fbx file.  This is NOT 3D PRINTABLE, and is intended for use in Unity or another 3D application.  It includes the antibodies, HA1 in surface and ribbon format, a membrane patch, and antibody binding sites and coordinating residues as separate meshes.

 The viewer version of the model (and other downloads) are a 3D Printable version of the surface model, membrane and antibodies. 

 

 

 

Render.jpg