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NIH3D

Fluticasone furoate

PubChem 9854489
was used by NIH 3D workflows to automatically generate models for
Felix
Created:
2/3/20
Submitted:
3/6/23
Published:
3/6/23

Select an image below to view

3DPX-012907

Licensing:

CC-BY
75
6
Version 2

Category

Small Molecules
Small Molecules
Description

Fluticasone furoate is a trifluorinated corticosteroid that consists of 6alpha,9-difluoro-11beta,17alpha-dihydroxy-17beta-{[(fluoromethyl)sulfanyl]carbonyl}-16-methyl-3-oxoandrosta-1,4-diene bearing a 2-furoyl substituent at position 17. Used in combination with vilanterol trifenate for treatment of bronchospasm associated with chronic obstructive pulmonary disease. It has a role as an anti-allergic agent, a prodrug and an anti-asthmatic drug. It is an 11beta-hydroxy steroid, a corticosteroid, a fluorinated steroid, a steroid ester, a 2-furoate ester, a thioester and a 3-oxo-Delta(1),Delta(4)-steroid. It is functionally related to a fluticasone. It derives from a hydride of an androstane.
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=9854489&width=400&height=400
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=9854489&width=400&height=400