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NIH3D

Topiramate

PubChem 5284627
was used by NIH 3D workflows to automatically generate models for
nadjkovic
Created:
10/3/19
Submitted:
3/6/23
Published:
3/6/23

Select an image below to view

3DPX-012100

Licensing:

CC-BY
49
3
Version 2

Category

Small Molecules
Small Molecules
Description

Topiramate is a hexose derivative that is 2,3:4,5-di-O-isopropylidene-beta-D-fructopyranose in which the hydroxy group has been converted to the corresponding sulfamate ester. It blocks voltage-dependent sodium channels and is used as an antiepileptic and for the prevention of migraine. It has a role as an anticonvulsant and a sodium channel blocker. It is a cyclic ketal, a sulfamate ester and a ketohexose derivative.