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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Ofloxacin

PubChem 4583
was used by NIH 3D workflows to automatically generate models for
Kzoghebi
Created:
9/30/19
Submitted:
10/8/26
Published:
10/8/26
ball-and-stick, color, print caution
4583-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-012060

NIH 3D DOI:

https://doi.org/10.60705/3dpx/12060.3

Licensing:

CC-BY
How to cite this NIH 3D entry
322
33
Version 3

Category

Small Molecules
Small Molecules
Description
Ofloxacin is a racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication. It has a role as an antiinfective agent, an antibacterial drug, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, a topoisomerase IV inhibitor and a DNA synthesis inhibitor. It is a racemate, a quinolone antibiotic and a fluoroquinolone antibiotic. It contains a dextrofloxacin and a levofloxacin.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=4583&width=400&height=400