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National Institute of Allergy and Infectious Disease
NIH 3D
FAQsBioArt

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NIH3D

Trametinib

PubChem 11707110
was used by NIH 3D workflows to automatically generate models for
Kzoghebi
Created:
2/17/19
Submitted:
10/7/26
Published:
10/7/26
ball-and-stick, color, print caution
11707110-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-010611

NIH 3D DOI:

https://doi.org/10.60705/3dpx/10611.3

Licensing:

CC-BY
How to cite this NIH 3D entry
311
16
Version 3

Category

Small Molecules
Small Molecules
Description
Trametinib is a pyridopyrimidine that is used (as its dimethyl sulfoxide addition compound) for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E or V600K mutations, and who have not received prior BRAF inhibitor treatment. It has a role as an anticoronaviral agent, a geroprotector, an antineoplastic agent and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a member of acetamides, an aromatic amine, a ring assembly, an organoiodine compound, an organofluorine compound, a pyridopyrimidine and a member of cyclopropanes.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=11707110&width=400&height=400