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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Tofacitinib

PubChem 9926791
was used by NIH 3D workflows to automatically generate models for
Kzoghebi
Created:
2/17/19
Submitted:
3/6/23
Published:
3/6/23
ball and stick, print caution
9926791-bas-color-print_NIH3DAtoms shown as ball-and-stick with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball and stick, print cautionsticks, not intended for 3D printingsticks, not intended for 3D printingsticks, print cautionspace-filled, print cautionspace-filled, print cautionball and stick, print cautionsticks, print caution
3DPX-010610

NIH 3D DOI:

https://doi.org/10.60705/3dpx/10610.2

Licensing:

CC-BY
How to cite this NIH 3D entry
69
4
Version 2

Category

Small Molecules
Small Molecules
Description
Tofacitinib is a pyrrolopyrimidine that is pyrrolo[2,3-d]pyrimidine substituted at position 4 by an N-methyl,N-(1-cyanoacetyl-4-methylpiperidin-3-yl)amino moiety. Used as its citrate salt to treat moderately to severely active rheumatoid arthritis. It has a role as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor and an antirheumatic drug. It is a pyrrolopyrimidine, a N-acylpiperidine, a nitrile and a tertiary amino compound.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=9926791&width=400&height=400
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=9926791&width=400&height=400