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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Sorafenib

PubChem 216239
was used by NIH 3D workflows to automatically generate models for
Kzoghebi
Created:
2/17/19
Submitted:
10/7/26
Published:
10/7/26
ball-and-stick, color, print caution
216239-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-010604

NIH 3D DOI:

https://doi.org/10.60705/3dpx/10604.3

Licensing:

CC-BY
How to cite this NIH 3D entry
278
18
Version 3

Category

Small Molecules
Small Molecules
Description
Sorafenib is a member of the class of phenylureas that is urea in which one of the nitrogens is substituted by a 4-chloro-3-trifluorophenyl group while the other is substituted by a phenyl group which, in turn, is substituted at the para position by a [2-(methylcarbamoyl)pyridin-4-yl]oxy group. It has a role as an anticoronaviral agent, a ferroptosis inducer, an antineoplastic agent, a tyrosine kinase inhibitor, an angiogenesis inhibitor and an EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor. It is a member of phenylureas, a pyridinecarboxamide, an aromatic ether, a member of monochlorobenzenes and a member of (trifluoromethyl)benzenes.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=216239&width=400&height=400