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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Pralatrexate

PubChem 148121
was used by NIH 3D workflows to automatically generate models for
Kzoghebi
Created:
2/17/19
Submitted:
10/7/26
Published:
10/7/26
ball-and-stick, color, print caution
148121-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-010598

NIH 3D DOI:

https://doi.org/10.60705/3dpx/10598.3

Licensing:

CC-BY
How to cite this NIH 3D entry
248
16
Version 3

Category

Small Molecules
Small Molecules
Description
Pralatrexate is a pteridine that is the N-4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl derivative of L-glutamic acid. Used for treatment of Peripheral T-Cell Lymphoma, an aggressive form of non-Hodgkins lymphoma. It has a role as an antimetabolite, an antineoplastic agent and an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. It is a N-acyl-L-glutamic acid, a member of pteridines and a terminal acetylenic compound.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=148121&width=400&height=400