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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Pralatrexate

PubChem 148121
was used by NIH 3D workflows to automatically generate models for
Kzoghebi
Created:
2/17/19
Submitted:
3/6/23
Published:
3/6/23
ball and stick, print caution
148121-bas-color-print_NIH3DAtoms shown as ball-and-stick with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball and stick, print cautionsticks, not intended for 3D printingsticks, not intended for 3D printingsticks, print cautionspace-filled, print cautionsticks, print cautionball and stick, print cautionspace-filled, print caution
3DPX-010598

NIH 3D DOI:

https://doi.org/10.60705/3dpx/10598.2

Licensing:

CC-BY
How to cite this NIH 3D entry
40
1
Version 2

Category

Small Molecules
Small Molecules
Description
Pralatrexate is a pteridine that is the N-4-[1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl]benzoyl derivative of L-glutamic acid. Used for treatment of Peripheral T-Cell Lymphoma, an aggressive form of non-Hodgkins lymphoma. It has a role as an antineoplastic agent, an antimetabolite and an EC 1.5.1.3 (dihydrofolate reductase) inhibitor. It is a N-acyl-L-glutamic acid, a member of pteridines and a terminal acetylenic compound.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=148121&width=400&height=400
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=148121&width=400&height=400