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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Palbociclib

PubChem 5330286
was used by NIH 3D workflows to automatically generate models for
Kzoghebi
Created:
2/17/19
Submitted:
10/7/26
Published:
10/7/26
ball-and-stick, color, print caution
5330286-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-010595

NIH 3D DOI:

https://doi.org/10.60705/3dpx/10595.3

Licensing:

CC-BY
How to cite this NIH 3D entry
244
24
Version 3

Category

Small Molecules
Small Molecules
Description
Palbociclib is a member of the class of pyridopyrimidines that is 2-{[5-(piperazin-1-yl)pyridin-2-yl]amino}pyrido[2,3-d]pyrimidin-7-one bearing additional methyl, acetyl and cyclopentyl substituents at positions 5, 6 and 8 respectively. It is used in combination with letrozole for the treatment of metastatic breast cancer. It has a role as an antineoplastic agent and an EC 2.7.11.22 (cyclin-dependent kinase) inhibitor. It is a member of cyclopentanes, a member of piperidines, an aminopyridine, a pyridopyrimidine, a secondary amino compound, a tertiary amino compound and an aromatic ketone.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=5330286&width=400&height=400