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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Carmustine

Generated by NIH 3D workflows using data provided by
Kzoghebi
Created:
2/17/19
Submitted:
2/17/19
Published:
2/17/19

This entry was migrated from the 3D Print Exchange and does not have a .glb file suitable for display in this viewer. You may download the .x3d files from this original entry from the Download button.

The most recent NIH3D processed version which has .glb files is avalilable from the version history.

3DPX-010561

Licensing:

CC-BY
How to cite this NIH 3D entry
96
7
Version 1

Category

Small Molecules
Small Molecules
Description

Carmustine is an antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood-brain barrier readily.

Source Data Details