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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Carmustine

Generated by NIH 3D workflows using data provided by
Kzoghebi
Created:
2/17/19
Submitted:
3/6/23
Published:
3/6/23
ball and stick, print caution
Carmustine-bas-color-print_NIH3DAtoms shown as ball-and-stick with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball and stick, print cautionsticks, not intended for 3D printingsticks, not intended for 3D printingsticks, print cautionspace-filled, print cautionspace-filled, print cautionball and stick, print cautionsticks, print caution
3DPX-010561

Licensing:

CC-BY
How to cite this NIH 3D entry
84
7
Version 2

Category

Small Molecules
Small Molecules
Description

Carmustine is an antineoplastic nitrosourea. Carmustine alkylates and cross-links DNA during all phases of the cell cycle, resulting in disruption of DNA function, cell cycle arrest, and apoptosis. This agent also carbamoylates proteins, including DNA repair enzymes, resulting in an enhanced cytotoxic effect. Carmustine is highly lipophilic and crosses the blood-brain barrier readily.

Source Data Details