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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Camptothecin

PubChem 24360
was used by NIH 3D workflows to automatically generate models for
Kzoghebi
Created:
2/17/19
Submitted:
3/6/23
Published:
3/6/23
ball and stick, print caution
24360-bas-color-print_NIH3DAtoms shown as ball-and-stick with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball and stick, print cautionsticks, not intended for 3D printingsticks, not intended for 3D printingsticks, print cautionspace-filled, print cautionsticks, print cautionspace-filled, print cautionball and stick, print caution
3DPX-010559

NIH 3D DOI:

https://doi.org/10.60705/3dpx/10559.2

Licensing:

CC-BY
How to cite this NIH 3D entry
52
2
Version 2

Category

Small Molecules
Small Molecules
Description
Camptothecin is a pyranoindolizinoquinoline that is pyrano[3',4':6,7]indolizino[1,2-b]quinoline which is substituted by oxo groups at positions 3 and 14, and by an ethyl group and a hydroxy group at position 4 (the S enantiomer). It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor, an antineoplastic agent, a genotoxin and a plant metabolite. It is a pyranoindolizinoquinoline, a tertiary alcohol, a delta-lactone and a quinoline alkaloid.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=24360&width=400&height=400
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=24360&width=400&height=400