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NIH3D

Camptothecin

PubChem 24360
was used by NIH 3D workflows to automatically generate models for
Kzoghebi
Created:
2/17/19
Submitted:
10/7/26
Published:
10/7/26

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Learn more about NIH 3D workflow outputs

3DPX-010559

Licensing:

CC-BY
289
18
Version 3

Category

Small Molecules
Small Molecules
Description

Camptothecin is a pyranoindolizinoquinoline that is pyrano[3',4':6,7]indolizino[1,2-b]quinoline which is substituted by oxo groups at positions 3 and 14, and by an ethyl group and a hydroxy group at position 4 (the S enantiomer). It has a role as an antineoplastic agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, a genotoxin and a plant metabolite. It is a delta-lactone, a quinoline alkaloid, a tertiary alcohol and a pyranoindolizinoquinoline.
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=24360&width=400&height=400