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NIH3D

Pazopanib

PubChem 10113978
was used by NIH 3D workflows to automatically generate models for
alex.sigaras
Created:
11/22/18
Submitted:
3/6/23
Published:
3/6/23

Select an image below to view

3DPX-010120

Licensing:

CC-BY
75
3
Version 2

Category

Small Molecules
Small Molecules
Description

Pazopanib is a pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor, a vascular endothelial growth factor receptor antagonist and an angiogenesis modulating agent. It is a member of indazoles, an aminopyrimidine and a sulfonamide. It is a conjugate base of a pazopanib(1+).
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=10113978&width=400&height=400
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=10113978&width=400&height=400