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National Institute of Allergy and Infectious Disease
NIH 3D
FAQsBioArt

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NIH3D

Pazopanib

PubChem 10113978
was used by NIH 3D workflows to automatically generate models for
alex.sigaras
Created:
11/22/18
Submitted:
10/7/26
Published:
10/7/26
ball-and-stick, color, print caution
10113978-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-010120

NIH 3D DOI:

https://doi.org/10.60705/3dpx/10120.3

Licensing:

CC-BY
How to cite this NIH 3D entry
275
19
Version 3

Category

Small Molecules
Small Molecules
Description
Pazopanib is a pyrimidine that is 5-(pyrimidin-2-yl}amino-2-methylbenzenesulfonamide substituted at position 4 by a (2,3-dimethylindazol-6-yl)(methyl)amino group. Used as its hydrochloride salt for treatment of kidney cancer. It has a role as an antineoplastic agent, a tyrosine kinase inhibitor, an angiogenesis modulating agent and a vascular endothelial growth factor receptor antagonist. It is a sulfonamide, an aminopyrimidine and a member of indazoles. It is a conjugate base of a pazopanib(1+).
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=10113978&width=400&height=400