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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Efavirenz

PubChem 64139
was used by NIH 3D workflows to automatically generate models for
Felixz
Created:
12/26/17
Submitted:
10/7/26
Published:
10/7/26
ball-and-stick, color, print caution
64139-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-008482

NIH 3D DOI:

https://doi.org/10.60705/3dpx/8482.3

Licensing:

CC-BY
How to cite this NIH 3D entry
562
18
Version 3

Category

Small Molecules
Small Molecules
Description
Efavirenz is 1,4-Dihydro-2H-3,1-benzoxazin-2-one substituted at the 4 position by cyclopropylethynyl and trifluoromethyl groups (S configuration) and at the 6 position by chlorine. A non-nucleoside reverse transcriptase inhibitor with activity against HIV, it is used with other antiretrovirals for combination therapy of HIV infection. It has a role as an antiviral drug and a HIV-1 reverse transcriptase inhibitor. It is an organochlorine compound, an organofluorine compound, a benzoxazine, a member of cyclopropanes and an acetylenic compound.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=64139&width=400&height=400