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NIH3D

Fenretinide

PubChem 5288209
was used by NIH 3D workflows to automatically generate models for
isabella
Created:
6/16/17
Submitted:
10/6/26
Published:
10/7/26

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Learn more about NIH 3D workflow outputs

3DPX-007444

Licensing:

Public Domain
295
31
Version 3

Category

Small Molecules
Small Molecules
Description

4-hydroxyphenyl retinamide is a retinoid obtained by formal condensation of the carboxy group of all-trans retinoic acid and the anilino group of 4-hydroxyaniline. Synthetic retinoid agonist. Antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Apoptotic effects appear to be mediated by a mechanism distinct from that of 'classical' retinoids. It has a role as an antioxidant and an antineoplastic agent. It is a retinoid and a monocarboxylic acid amide. It is functionally related to an all-trans-retinoic acid.
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=5288209&width=400&height=400