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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

CID 23

PubChem 23
was used by NIH 3D workflows to automatically generate models for
Jwoozy
Created:
5/31/17
Submitted:
3/6/23
Published:
3/6/23
ball and stick, print caution
23-bas-color-print_NIH3DAtoms shown as ball-and-stick with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball and stick, print cautionsticks, not intended for 3D printingsticks, not intended for 3D printingsticks, print cautionspace-filled, print cautionspace-filled, print cautionball and stick, print cautionsticks, print caution
3DPX-005140

NIH 3D DOI:

https://doi.org/10.60705/3dpx/5140.2

Licensing:

Public Domain
How to cite this NIH 3D entry
30
1
Version 2

Category

Small Molecules
Small Molecules
Description
2-amino-3-carboxymuconic acid semialdehyde is an intermediate metabolite of the tryptophan-niacin catabolic pathway. Current interest in the degradation of tryptophan is mostly due to the role of quinolinate and other metabolites in several neuropathological conditions. Quinolinate is a neurotoxin formed nonenzymatically from 2-amino-3-carboxymuconic semialdehyde in mammalian tissues. 2-Amino-3-carboxymuconic semialdehyde is enzymatically converted to 2-aminomuconate via 2-aminomuconic semialdehyde. (PMID: 10510494, 16267312, 14275129).
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=23&width=400&height=400
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=23&width=400&height=400