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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

2-Amino-3-(3-oxo-1-propen-1-yl)-2-butenedioic acid

PubChem 23
was used by NIH 3D workflows to automatically generate models for
Jwoozy
Created:
5/31/17
Submitted:
10/6/26
Published:
10/7/26
ball-and-stick, color, print caution
23-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

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ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-005140

NIH 3D DOI:

https://doi.org/10.60705/3dpx/5140.3

Licensing:

Public Domain
How to cite this NIH 3D entry
195
33
Version 3

Category

Small Molecules
Small Molecules
Description
2-amino-3-carboxymuconic acid semialdehyde is an intermediate metabolite of the tryptophan-niacin catabolic pathway. Current interest in the degradation of tryptophan is mostly due to the role of quinolinate and other metabolites in several neuropathological conditions. Quinolinate is a neurotoxin formed nonenzymatically from 2-amino-3-carboxymuconic semialdehyde in mammalian tissues. 2-Amino-3-carboxymuconic semialdehyde is enzymatically converted to 2-aminomuconate via 2-aminomuconic semialdehyde. (PMID: 10510494, 16267312, 14275129).
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=23&width=400&height=400