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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Phevalin

PubChem 10376483
was used by NIH 3D workflows to automatically generate models for
suzyq
Created:
2/22/17
Submitted:
10/6/26
Published:
10/6/26
ball-and-stick, color, print caution
10376483-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-004582

NIH 3D DOI:

https://doi.org/10.60705/3dpx/4582.3

Licensing:

Public Domain
How to cite this NIH 3D entry
194
18
Version 3

Category

Small Molecules
Small Molecules
Description
Phevalin is a member of the class of pyrazinones that is pyrazin-2(1H)-one substituted by an isopropyl and benzyl groups at position 3 and 6, respectively. It is a natural product found in Staphylococcus aureus that inhibits calpain in a casein hydrolysis assay (IC50 = 1.3 M), contributes to S. aureus infection in mice, and alters human keratinocyte gene expression. It has a role as a bacterial metabolite and a calpain inhibitor. It is a pyrazinone and a member of benzenes.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=10376483&width=400&height=400