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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Naloxone

PubChem 5284596
was used by NIH 3D workflows to automatically generate models for
emckinst
Created:
11/21/16
Submitted:
10/6/26
Published:
10/6/26
ball-and-stick, color, print caution
5284596-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-004184

NIH 3D DOI:

https://doi.org/10.60705/3dpx/4184.3

Licensing:

Public Domain
How to cite this NIH 3D entry
524
37
Version 3

Category

Small Molecules
Small Molecules
Description
Naloxone is a synthetic morphinane alkaloid that is morphinone in which the enone double bond has been reduced to a single bond, the hydrogen at position 14 has been replaced by a hydroxy group, and the methyl group attached to the nitrogen has been replaced by an allyl group. A specific opioid antagonist, it is used (commonly as its hydrochloride salt) to reverse the effects of opioids, both following their use of opioids during surgery and in cases of known or suspected opioid overdose. It has a role as a central nervous system depressant, a mu-opioid receptor antagonist and an antidote to opioid poisoning. It is a morphinane alkaloid, a tertiary alcohol and an organic heteropentacyclic compound. It is a conjugate base of a naloxone(1+). It derives from a hydride of a morphinan.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=5284596&width=400&height=400