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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Memantine

PubChem 4054
was used by NIH 3D workflows to automatically generate models for
nevitdilmen
Created:
11/9/16
Submitted:
10/6/26
Published:
10/6/26
ball-and-stick, color, print caution
4054-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-004101

NIH 3D DOI:

https://doi.org/10.60705/3dpx/4101.3

Licensing:

Public Domain
How to cite this NIH 3D entry
361
20
Version 3

Category

Small Molecules
Small Molecules
Description
Memantine is a primary aliphatic amine that is the 3,5-dimethyl derivative of 1-aminoadamantane. A low to moderate affinity uncompetitive (open-channel); NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels. It has a role as an antidepressant, an antiparkinson drug, a dopaminergic agent, a NMDA receptor antagonist and a neuroprotective agent. It is a primary aliphatic amine and a member of adamantanes. It is a conjugate base of a memantinium(1+). It derives from a hydride of an adamantane.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=4054&width=400&height=400